On March 21, 2019, California’s Office of Environmental Health Hazard Assessment (OEHHA) has established Proposition 65 maximum allowable dose levels (MADLs) for oral and inhalation exposures to n-hexane. The regulation will take effect from July 1, 2019.


The MADLs for n-hexane have been set at:

  1. 28000 micrograms per day for oral exposure
  2. 20000 micrograms per day for inhalation exposure

An MADL represents a safe harbour exposure limit below which a company is not required to provide a Prop 65 warning.

N-hexane is used a degreaser, solvent component and low-temperature thermometer filling. It was listed as a reproductive toxicant under Prop 65 in December 2017.



|Further Information:

Amendment to Prop 65 Maximum Allowable Dose Levels for n-Hexane

Maximum Allowable Dose Levels for n-Hexane (Oral and Inhalation)

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Prop 65